{"id":6710,"date":"2022-12-01T17:07:00","date_gmt":"2022-12-01T12:07:00","guid":{"rendered":"https:\/\/www.serenepharma.com\/?p=6710"},"modified":"2023-02-06T17:13:52","modified_gmt":"2023-02-06T12:13:52","slug":"prognosticheskoe-znachenie-globalnoj","status":"publish","type":"post","link":"https:\/\/www.serenepharma.com\/ru\/gazetaru\/prognosticheskoe-znachenie-globalnoj\/","title":{"rendered":"\u041f\u0440\u043e\u0433\u043d\u043e\u0441\u0442\u0438\u0447\u0435\u0441\u043a\u043e\u0435 \u0437\u043d\u0430\u0447\u0435\u043d\u0438\u0435 \u0433\u043b\u043e\u0431\u0430\u043b\u044c\u043d\u043e\u0439 \u043f\u0440\u043e\u0434\u043e\u043b\u044c\u043d\u043e\u0439 \u0434\u0435\u0444\u043e\u0440\u043c\u0430\u0446\u0438\u0438 \u0443 \u043f\u0430\u0446\u0438\u0435\u043d\u0442\u043e\u0432 \u0441 \u0441\u0435\u0440\u0434\u0435\u0447\u043d\u043e\u0439 \u043d\u0435\u0434\u043e\u0441\u0442\u0430\u0442\u043e\u0447\u043d\u043e\u0441\u0442\u044c\u044e \u0441 \u0443\u043b\u0443\u0447\u0448\u0435\u043d\u043d\u043e\u0439 \u0444\u0440\u0430\u043a\u0446\u0438\u0435\u0439 \u0432\u044b\u0431\u0440\u043e\u0441\u0430"},"content":{"rendered":"\n<blockquote class=\"wp-block-quote is-layout-flow wp-block-quote-is-layout-flow\"><p><strong>\u0421\u0441\u044b\u043b\u043a\u0430: <\/strong>\u0421\u0430\u0442\u0438\u0442 \u0414\u0436\u0430\u043d\u0432\u0430\u043d\u0438\u0448\u0441\u0442\u0430\u043f\u043e\u0440\u043d, \u0416\u0410\u041a\u041a \u0421\u0435\u0440\u0434\u0435\u0447\u043d\u0430\u044f \u043d\u0435\u0434\u043e\u0441\u0442\u0430\u0442\u043e\u0447\u043d\u043e\u0441\u0442\u044c. 2022 \u044f\u043d\u0432\u0430\u0440\u044c;10(1):27-37. doi: 10.1016\/j.jchf.2021.08.007. Epub 2021 10 \u043d\u043e\u044f\u0431\u0440\u044f.<\/p><\/blockquote>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u0412\u0441\u0442\u0443\u043f\u043b\u0435\u043d\u0438\u0435<\/strong><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">\u041f\u0430\u0446\u0438\u0435\u043d\u0442\u044b \u0441\u043e \u0441\u043d\u0438\u0436\u0435\u043d\u043d\u043e\u0439 \u0444\u0440\u0430\u043a\u0446\u0438\u0435\u0439 \u0432\u044b\u0431\u0440\u043e\u0441\u0430 (\u0424\u0412) \u0447\u0430\u0441\u0442\u043e \u0434\u0435\u043c\u043e\u043d\u0441\u0442\u0440\u0438\u0440\u0443\u044e\u0442 \u0443\u043b\u0443\u0447\u0448\u0435\u043d\u0438\u0435 \u0424\u0412 \u043b\u0435\u0432\u043e\u0433\u043e \u0436\u0435\u043b\u0443\u0434\u043e\u0447\u043a\u0430 (\u0424\u0412\u041b\u0416). \u041f\u0430\u0446\u0438\u0435\u043d\u0442\u044b, \u0443 \u043a\u043e\u0442\u043e\u0440\u044b\u0445 \u0424\u0412\u041b\u0416 \u0443\u0432\u0435\u043b\u0438\u0447\u0438\u0432\u0430\u0435\u0442\u0441\u044f \u0432 \u0430\u0431\u0441\u043e\u043b\u044e\u0442\u043d\u043e\u043c \u0432\u044b\u0440\u0430\u0436\u0435\u043d\u0438\u0438 \u043d\u0430 10% \u0438\u043b\u0438 \u226540% \u043f\u043e \u0441\u0440\u0430\u0432\u043d\u0435\u043d\u0438\u044e \u0441 \u0438\u0441\u0445\u043e\u0434\u043d\u044b\u043c \u0443\u0440\u043e\u0432\u043d\u0435\u043c &lt;40%, \u043e\u0442\u043d\u043e\u0441\u044f\u0442\u0441\u044f \u043a \u043a\u0430\u0442\u0435\u0433\u043e\u0440\u0438\u0438 \u043f\u0430\u0446\u0438\u0435\u043d\u0442\u043e\u0432 \u0441 \u0441\u0435\u0440\u0434\u0435\u0447\u043d\u043e\u0439 \u043d\u0435\u0434\u043e\u0441\u0442\u0430\u0442\u043e\u0447\u043d\u043e\u0441\u0442\u044c\u044e \u0441 \u0443\u043b\u0443\u0447\u0448\u0435\u043d\u043d\u043e\u0439 \u0424\u0412 (\u0421\u041d\u0443\u043b\u0443\u0447\u0424\u0412). \u041f\u0430\u0446\u0438\u0435\u043d\u0442\u044b \u0441 \u0421\u041d\u0443\u043b\u0443\u0447\u0424\u0412 \u0438\u043c\u0435\u044e\u0442 \u0440\u0430\u0437\u043b\u0438\u0447\u043d\u043e\u0435 \u043a\u043b\u0438\u043d\u0438\u0447\u0435\u0441\u043a\u043e\u0435 \u0442\u0435\u0447\u0435\u043d\u0438\u0435. \u0413\u043b\u043e\u0431\u0430\u043b\u044c\u043d\u0430\u044f \u043f\u0440\u043e\u0434\u043e\u043b\u044c\u043d\u0430\u044f \u0434\u0435\u0444\u043e\u0440\u043c\u0430\u0446\u0438\u044f (\u0413\u041f\u0414), \u0447\u0443\u0432\u0441\u0442\u0432\u0438\u0442\u0435\u043b\u044c\u043d\u044b\u0439 \u043f\u043e\u043a\u0430\u0437\u0430\u0442\u0435\u043b\u044c \u0441\u0438\u0441\u0442\u043e\u043b\u0438\u0447\u0435\u0441\u043a\u043e\u0439 \u0444\u0443\u043d\u043a\u0446\u0438\u0438 \u041b\u0416, \u043c\u043e\u0436\u0435\u0442 \u0431\u044b\u0442\u044c \u0446\u0435\u043d\u043d\u044b\u043c \u043f\u0440\u043e\u0433\u043d\u043e\u0437\u043e\u043c \u0440\u0438\u0441\u043a\u0430 \u0431\u0443\u0434\u0443\u0449\u0438\u0445 \u0441\u043e\u0431\u044b\u0442\u0438\u0439 \u0432 \u044d\u0442\u043e\u0439 \u043f\u043e\u0434\u0433\u0440\u0443\u043f\u043f\u0435 \u043f\u0430\u0446\u0438\u0435\u043d\u0442\u043e\u0432.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u0426\u0435\u043b\u044c<\/strong><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">\u041e\u043f\u0440\u0435\u0434\u0435\u043b\u0438\u0442\u044c, \u0431\u0443\u0434\u0435\u0442 \u043b\u0438 \u0413\u041f\u0414 \u043d\u0435\u0437\u0430\u0432\u0438\u0441\u0438\u043c\u043e \u043f\u0440\u0435\u0434\u0441\u043a\u0430\u0437\u044b\u0432\u0430\u0442\u044c \u0431\u0443\u0434\u0443\u0449\u0438\u0435 \u043a\u043b\u0438\u043d\u0438\u0447\u0435\u0441\u043a\u0438\u0435 \u0441\u043e\u0431\u044b\u0442\u0438\u044f \u0443 \u043f\u0430\u0446\u0438\u0435\u043d\u0442\u043e\u0432 \u0441 \u0421\u041d\u0443\u043b\u0443\u0447\u0424\u0412<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u041e\u0446\u0435\u043d\u043a\u0430<\/strong><\/h3>\n\n\n\n<ul class=\"wp-block-list\"><li>\u0413\u041f\u0414 \u043e\u0446\u0435\u043d\u0438\u0432\u0430\u043b\u0438 \u0441 \u0438\u0441\u043f\u043e\u043b\u044c\u0437\u043e\u0432\u0430\u043d\u0438\u0435\u043c 2-\u043c\u0435\u0440\u043d\u043e\u0433\u043e \u043f\u0440\u043e\u0433\u0440\u0430\u043c\u043c\u043d\u043e\u0433\u043e \u043e\u0431\u0435\u0441\u043f\u0435\u0447\u0435\u043d\u0438\u044f \u0434\u043b\u044f \u043e\u0442\u0441\u043b\u0435\u0436\u0438\u0432\u0430\u043d\u0438\u044f \u0441\u043f\u0435\u043a\u043b\u043e\u0432 \u043f\u0440\u0438 \u0438\u043d\u0434\u0435\u043a\u0441\u043d\u043e\u0439 \u044d\u0445\u043e\u043a\u0430\u0440\u0434\u0438\u043e\u0433\u0440\u0430\u0444\u0438\u0438<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u0420\u0435\u0437\u0443\u043b\u044c\u0442\u0430\u0442\u044b<\/strong><\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>\u0421\u0440\u0435\u0434\u043d\u0438\u0439 \u0432\u043e\u0437\u0440\u0430\u0441\u0442 \u0438\u0441\u0441\u043b\u0435\u0434\u0443\u0435\u043c\u043e\u0439 \u043f\u043e\u043f\u0443\u043b\u044f\u0446\u0438\u0438 \u0441\u043e\u0441\u0442\u0430\u0432\u0438\u043b 64 \u0433\u043e\u0434\u0430, 70% \u0441\u043e\u0441\u0442\u0430\u0432\u043b\u044f\u043b\u0438 \u043c\u0443\u0436\u0447\u0438\u043d\u044b, 68,5% \u0438\u043c\u0435\u043b\u0438 \u043d\u0435\u0438\u0448\u0435\u043c\u0438\u0447\u0435\u0441\u043a\u0443\u044e \u044d\u0442\u0438\u043e\u043b\u043e\u0433\u0438\u044e \u0438 75,9% \u0438\u043c\u0435\u043b\u0438 \u0441\u0438\u043c\u043f\u0442\u043e\u043c\u044b I \u0438\u043b\u0438 II \u0444\u0443\u043d\u043a\u0446\u0438\u043e\u043d\u0430\u043b\u044c\u043d\u043e\u0433\u043e \u043a\u043b\u0430\u0441\u0441\u0430 \u041d\u044c\u044e-\u0419\u043e\u0440\u043a\u0441\u043a\u043e\u0439 \u0430\u0441\u0441\u043e\u0446\u0438\u0430\u0446\u0438\u0438 \u0441\u0435\u0440\u0434\u0446\u0430 (\u041d\u0419\u0410\u0421).<\/li><li>\u041c\u0435\u0434\u0438\u0430\u043d\u0430 \u0432\u0440\u0435\u043c\u0435\u043d\u0438 \u043e\u0442 \u043f\u0435\u0440\u0432\u043e\u0433\u043e \u0434\u0438\u0430\u0433\u043d\u043e\u0437\u0430 \u0421\u041d \u0434\u043e \u0438\u043d\u0434\u0435\u043a\u0441\u043d\u043e\u0439 \u044d\u0445\u043e\u043a\u0430\u0440\u0434\u0438\u043e\u0433\u0440\u0430\u0444\u0438\u0438 \u0441\u043e\u0441\u0442\u0430\u0432\u0438\u043b\u0430 22 \u043c\u0435\u0441\u044f\u0446\u0430, \u043c\u0435\u0434\u0438\u0430\u043d\u0430 \u0430\u0431\u0441\u043e\u043b\u044e\u0442\u043d\u044b\u0445 \u0437\u043d\u0430\u0447\u0435\u043d\u0438\u0439 \u0413\u041f\u0414 (aGLS) \u0438 \u0424\u0412\u041b\u0416 \u043f\u043e \u0434\u0430\u043d\u043d\u044b\u043c \u0438\u043d\u0434\u0435\u043a\u0441\u043d\u043e\u0439 \u044d\u0445\u043e\u043a\u0430\u0440\u0434\u0438\u043e\u0433\u0440\u0430\u0444\u0438\u0438 \u0441\u043e\u0441\u0442\u0430\u0432\u0438\u043b\u0430 12,7% \u0438 52% \u0441\u043e\u043e\u0442\u0432\u0435\u0442\u0441\u0442\u0432\u0435\u043d\u043d\u043e.<\/li><li>\u0427\u0430\u0441\u0442\u043e\u0442\u0430 \u043f\u0435\u0440\u0432\u0438\u0447\u043d\u044b\u0445 \u0438\u0441\u0445\u043e\u0434\u043e\u0432 \u0432 \u0442\u0435\u0447\u0435\u043d\u0438\u0435 53 \u043c\u0435\u0441\u044f\u0446\u0435\u0432 \u043f\u043e\u0441\u043b\u0435 \u0438\u043d\u0434\u0435\u043a\u0441\u043d\u043e\u0439 \u044d\u0445\u043e\u043a\u0430\u0440\u0434\u0438\u043e\u0433\u0440\u0430\u0444\u0438\u0438 \u0431\u044b\u043b\u0430 \u0440\u0435\u0436\u0435 \u0443 \u043f\u0430\u0446\u0438\u0435\u043d\u0442\u043e\u0432 \u0441 aGLS \u0432\u044b\u0448\u0435 \u043c\u0435\u0434\u0438\u0430\u043d\u044b, \u0447\u0435\u043c \u043d\u0438\u0436\u0435 \u043d\u0435\u0435 (\u0440\u0438\u0441. 1).<\/li><li>\u041e\u0446\u0435\u043d\u043a\u0430 \u0432 \u043a\u0430\u0447\u0435\u0441\u0442\u0432\u0435 \u043d\u0435\u043f\u0440\u0435\u0440\u044b\u0432\u043d\u043e\u0439 \u043f\u0435\u0440\u0435\u043c\u0435\u043d\u043d\u043e\u0439 \u043f\u043e\u043a\u0430\u0437\u0430\u043b\u0430, \u0447\u0442\u043e \u043a\u0430\u0436\u0434\u043e\u0435 \u0443\u0432\u0435\u043b\u0438\u0447\u0435\u043d\u0438\u0435 aGLS \u043d\u0430 1% \u043d\u0430 \u0438\u043d\u0434\u0435\u043a\u0441\u043d\u043e\u0439 \u044d\u0445\u043e\u043a\u0430\u0440\u0434\u0438\u043e\u0433\u0440\u0430\u043c\u043c\u0435 \u0431\u044b\u043b\u043e \u0441\u0432\u044f\u0437\u0430\u043d\u043e \u0441 \u043c\u0435\u043d\u044c\u0448\u0435\u0439 \u0432\u0435\u0440\u043e\u044f\u0442\u043d\u043e\u0441\u0442\u044c\u044e \u043a\u043e\u043c\u0431\u0438\u043d\u0438\u0440\u043e\u0432\u0430\u043d\u043d\u043e\u0433\u043e \u0438\u0441\u0445\u043e\u0434\u0430 (K\u0420; 0,86, 95% \u0414\u0418; 0,79-0,93, \u0420 &lt;0,001). \u0410\u0441\u0441\u043e\u0446\u0438\u0430\u0446\u0438\u044f \u0441\u043e\u0445\u0440\u0430\u043d\u044f\u043b\u0430\u0441\u044c \u0438 \u043f\u043e\u0441\u043b\u0435 \u043c\u043d\u043e\u0433\u043e\u0444\u0430\u043a\u0442\u043e\u0440\u043d\u043e\u0439 \u043a\u043e\u0440\u0440\u0435\u043a\u0442\u0438\u0440\u043e\u0432\u043a\u0438 (K\u0420; 0,90, 95% \u0414\u0418; 0,82-0,97, \u0420=0,01).<\/li><li>\u0421\u043d\u0438\u0436\u0435\u043d\u0438\u0435 \u0424\u0412\u041b\u0416 \u043e\u0442 >5% \u0434\u043e &lt;40% \u043d\u0430\u0431\u043b\u044e\u0434\u0430\u043b\u043e\u0441\u044c \u0443 88 (38,6%) \u043f\u0430\u0446\u0438\u0435\u043d\u0442\u043e\u0432. \u0422\u0430\u043a\u0438\u043c \u043e\u0431\u0440\u0430\u0437\u043e\u043c, \u0441\u043d\u0438\u0436\u0435\u043d\u0438\u0435 aGLS \u0430\u0441\u0441\u043e\u0446\u0438\u0438\u0440\u043e\u0432\u0430\u043b\u043e\u0441\u044c \u0441 \u043f\u043e\u0432\u044b\u0448\u0435\u043d\u043d\u043e\u0439 \u0432\u0435\u0440\u043e\u044f\u0442\u043d\u043e\u0441\u0442\u044c\u044e \u0443\u0445\u0443\u0434\u0448\u0435\u043d\u0438\u044f \u0424\u0412\u041b\u0416; \u0443\u0445\u0443\u0434\u0448\u0435\u043d\u0438\u0435 \u0424\u0412\u041b\u0416 \u0447\u0430\u0449\u0435 \u043d\u0430\u0431\u043b\u044e\u0434\u0430\u043b\u043e\u0441\u044c \u0443 \u043f\u0430\u0446\u0438\u0435\u043d\u0442\u043e\u0432 \u0441 aGLS \u043d\u0438\u0436\u0435 \u043c\u0435\u0434\u0438\u0430\u043d\u044b \u043f\u043e \u0441\u0440\u0430\u0432\u043d\u0435\u043d\u0438\u044e \u0441 \u043f\u0430\u0446\u0438\u0435\u043d\u0442\u0430\u043c\u0438 \u0441 aGLS \u0432\u044b\u0448\u0435 \u043c\u0435\u0434\u0438\u0430\u043d\u044b (49,6% \u043f\u0440\u043e\u0442\u0438\u0432 25,7%, \u0420 &lt;0,001).<\/li><li>\u041f\u0430\u0446\u0438\u0435\u043d\u0442\u044b \u0441 \u0424\u0412\u041b\u0416 \u043d\u0438\u0436\u0435 \u043c\u0435\u0434\u0438\u0430\u043d\u044b \u043f\u0440\u0438 \u0438\u043d\u0434\u0435\u043a\u0441\u043d\u043e\u0439 \u044d\u0445\u043e\u043a\u0430\u0440\u0434\u0438\u043e\u0433\u0440\u0430\u0444\u0438\u0438 \u0438\u043c\u0435\u043b\u0438 \u0431\u043e\u043b\u0435\u0435 \u0432\u044b\u0441\u043e\u043a\u0443\u044e \u0447\u0430\u0441\u0442\u043e\u0442\u0443 \u0416\u0422 \u0438\u043b\u0438 \u0441\u043e\u043e\u0442\u0432\u0435\u0442\u0441\u0442\u0432\u0443\u044e\u0449\u0435\u0433\u043e \u0448\u043e\u043a\u0430 \u043e\u0442 \u0418\u041a\u0414 (6,4% \u043f\u0440\u043e\u0442\u0438\u0432 1,9%; \u0420=0,047) \u0432\u043e \u0432\u0440\u0435\u043c\u044f \u043f\u043e\u0441\u043b\u0435\u0434\u0443\u044e\u0449\u0435\u0433\u043e \u043d\u0430\u0431\u043b\u044e\u0434\u0435\u043d\u0438\u044f.<\/li><\/ul>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-large is-resized\"><a href=\"https:\/\/www.serenepharma.com\/wp-content\/uploads\/2023\/02\/5ru2.jpg\"><img fetchpriority=\"high\" decoding=\"async\" src=\"https:\/\/www.serenepharma.com\/wp-content\/uploads\/2023\/02\/5ru2-1024x637.jpg\" alt=\"\" class=\"wp-image-6711\" width=\"441\" height=\"274\" srcset=\"https:\/\/www.serenepharma.com\/wp-content\/uploads\/2023\/02\/5ru2-1024x637.jpg 1024w, https:\/\/www.serenepharma.com\/wp-content\/uploads\/2023\/02\/5ru2-300x187.jpg 300w, https:\/\/www.serenepharma.com\/wp-content\/uploads\/2023\/02\/5ru2-768x478.jpg 768w, https:\/\/www.serenepharma.com\/wp-content\/uploads\/2023\/02\/5ru2-1536x955.jpg 1536w, https:\/\/www.serenepharma.com\/wp-content\/uploads\/2023\/02\/5ru2-2048x1274.jpg 2048w, https:\/\/www.serenepharma.com\/wp-content\/uploads\/2023\/02\/5ru2-600x373.jpg 600w\" sizes=\"(max-width: 441px) 100vw, 441px\" \/><\/a><\/figure>\n<\/div>\n\n\n<h2 class=\"wp-block-heading\"><strong>\u0412\u044b\u0432\u043e\u0434\u044b<\/strong><\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>\u041f\u0430\u0446\u0438\u0435\u043d\u0442\u044b \u0441 \u0421\u041d\u0443\u043b\u0443\u0447\u0424\u0412 \u0438\u043c\u0435\u043b\u0438 \u043b\u0443\u0447\u0448\u0438\u0439 \u043f\u0440\u043e\u0433\u043d\u043e\u0437 \u043f\u043e \u0441\u0440\u0430\u0432\u043d\u0435\u043d\u0438\u044e \u0441 \u043f\u0430\u0446\u0438\u0435\u043d\u0442\u0430\u043c\u0438 \u0441 \u0443\u0441\u0442\u043e\u0439\u0447\u0438\u0432\u043e \u043d\u0438\u0437\u043a\u043e\u0439 \u0424\u0412\u041b\u0416. \u0423 \u0442\u0430\u043a\u0438\u0445 \u043f\u0430\u0446\u0438\u0435\u043d\u0442\u043e\u0432 \u0431\u044b\u043b \u043d\u0438\u0437\u043a\u0438\u0439 \u0440\u0438\u0441\u043a \u0443\u0445\u0443\u0434\u0448\u0435\u043d\u0438\u044f \u0421\u041d, \u0441\u043c\u0435\u0440\u0442\u0438 \u043e\u0442 \u0441\u0435\u0440\u0434\u0435\u0447\u043d\u043e-\u0441\u043e\u0441\u0443\u0434\u0438\u0441\u0442\u044b\u0445 \u0437\u0430\u0431\u043e\u043b\u0435\u0432\u0430\u043d\u0438\u0439 \u0438 \u0431\u0443\u0434\u0443\u0449\u0435\u0433\u043e \u0443\u0445\u0443\u0434\u0448\u0435\u043d\u0438\u044f \u0441\u0435\u0440\u0434\u0435\u0447\u043d\u043e\u0439 \u0444\u0443\u043d\u043a\u0446\u0438\u0438.<\/li><li>\u0413\u041f\u0414 \u0431\u044b\u043b \u0441\u0438\u043b\u044c\u043d\u044b\u043c \u0438 \u043d\u0435\u0437\u0430\u0432\u0438\u0441\u0438\u043c\u044b\u043c \u043f\u0440\u043e\u0433\u043d\u043e\u0437\u043e\u043c \u0431\u0443\u0434\u0443\u0449\u0438\u0445 \u0441\u043e\u0431\u044b\u0442\u0438\u0439 \u0421\u041d \u0438 \u0443\u0445\u0443\u0434\u0448\u0435\u043d\u0438\u044f \u0441\u0435\u0440\u0434\u0435\u0447\u043d\u043e\u0439 \u0444\u0443\u043d\u043a\u0446\u0438\u0438 \u0443 \u043f\u0430\u0446\u0438\u0435\u043d\u0442\u043e\u0432 \u0441 \u0421\u041d\u0443\u043b\u0443\u0447\u0424\u0412.<\/li><li>\u041f\u043e\u044d\u0442\u043e\u043c\u0443 \u0432\u0430\u0436\u043d\u043e \u0441\u043b\u0435\u0434\u0438\u0442\u044c \u0437\u0430 \u0443\u0445\u0443\u0434\u0448\u0435\u043d\u0438\u0435\u043c \u0441\u043e\u0441\u0442\u043e\u044f\u043d\u0438\u044f \u0443 \u043f\u0430\u0446\u0438\u0435\u043d\u0442\u043e\u0432 \u0441 \u043d\u0430\u0440\u0443\u0448\u0435\u043d\u043d\u043e\u0439 \u0413\u041f\u0414, \u043d\u0435\u0441\u043c\u043e\u0442\u0440\u044f \u043d\u0430 \u043d\u043e\u0440\u043c\u0430\u043b\u0438\u0437\u0430\u0446\u0438\u044e \u0424\u0412\u041b\u0416.<\/li><\/ul>\n","protected":false},"excerpt":{"rendered":"<p>\u0421\u0441\u044b\u043b\u043a\u0430: \u0421\u0430\u0442\u0438\u0442 \u0414\u0436\u0430\u043d\u0432\u0430\u043d\u0438\u0448\u0441\u0442\u0430\u043f\u043e\u0440\u043d, \u0416\u0410\u041a\u041a \u0421\u0435\u0440\u0434\u0435\u0447\u043d\u0430\u044f \u043d\u0435\u0434\u043e\u0441\u0442\u0430\u0442\u043e\u0447\u043d\u043e\u0441\u0442\u044c. 2022 \u044f\u043d\u0432\u0430\u0440\u044c;10(1):27-37. doi: 10.1016\/j.jchf.2021.08.007. Epub 2021 10 \u043d\u043e\u044f\u0431\u0440\u044f. \u0412\u0441\u0442\u0443\u043f\u043b\u0435\u043d\u0438\u0435 \u041f\u0430\u0446\u0438\u0435\u043d\u0442\u044b \u0441\u043e \u0441\u043d\u0438\u0436\u0435\u043d\u043d\u043e\u0439 \u0444\u0440\u0430\u043a\u0446\u0438\u0435\u0439 \u0432\u044b\u0431\u0440\u043e\u0441\u0430 (\u0424\u0412) \u0447\u0430\u0441\u0442\u043e \u0434\u0435\u043c\u043e\u043d\u0441\u0442\u0440\u0438\u0440\u0443\u044e\u0442 \u0443\u043b\u0443\u0447\u0448\u0435\u043d\u0438\u0435 \u0424\u0412 \u043b\u0435\u0432\u043e\u0433\u043e \u0436\u0435\u043b\u0443\u0434\u043e\u0447\u043a\u0430 (\u0424\u0412\u041b\u0416). \u041f\u0430\u0446\u0438\u0435\u043d\u0442\u044b, \u0443 \u043a\u043e\u0442\u043e\u0440\u044b\u0445 \u0424\u0412\u041b\u0416 \u0443\u0432\u0435\u043b\u0438\u0447\u0438\u0432\u0430\u0435\u0442\u0441\u044f \u0432 \u0430\u0431\u0441\u043e\u043b\u044e\u0442\u043d\u043e\u043c \u0432\u044b\u0440\u0430\u0436\u0435\u043d\u0438\u0438 \u043d\u0430 10% \u0438\u043b\u0438 \u226540% \u043f\u043e \u0441\u0440\u0430\u0432\u043d\u0435\u043d\u0438\u044e \u0441 \u0438\u0441\u0445\u043e\u0434\u043d\u044b\u043c \u0443\u0440\u043e\u0432\u043d\u0435\u043c &lt;40%, \u043e\u0442\u043d\u043e\u0441\u044f\u0442\u0441\u044f \u043a \u043a\u0430\u0442\u0435\u0433\u043e\u0440\u0438\u0438 \u043f\u0430\u0446\u0438\u0435\u043d\u0442\u043e\u0432 \u0441 \u0441\u0435\u0440\u0434\u0435\u0447\u043d\u043e\u0439 \u043d\u0435\u0434\u043e\u0441\u0442\u0430\u0442\u043e\u0447\u043d\u043e\u0441\u0442\u044c\u044e \u0441 \u0443\u043b\u0443\u0447\u0448\u0435\u043d\u043d\u043e\u0439&#8230;<\/p>\n","protected":false},"author":1,"featured_media":6712,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"rs_blank_template":"","rs_page_bg_color":"","slide_template_v7":"","inline_featured_image":false,"footnotes":""},"categories":[140],"tags":[159],"class_list":["post-6710","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-gazetaru","tag-kardiologija"],"acf":[],"aioseo_notices":[],"aioseo_head":"\n\t\t<!-- All in One SEO 4.9.10 - aioseo.com -->\n\t<meta name=\"description\" content=\"\u0421\u0441\u044b\u043b\u043a\u0430: \u0421\u0430\u0442\u0438\u0442 \u0414\u0436\u0430\u043d\u0432\u0430\u043d\u0438\u0448\u0441\u0442\u0430\u043f\u043e\u0440\u043d, \u0416\u0410\u041a\u041a \u0421\u0435\u0440\u0434\u0435\u0447\u043d\u0430\u044f \u043d\u0435\u0434\u043e\u0441\u0442\u0430\u0442\u043e\u0447\u043d\u043e\u0441\u0442\u044c. 2022 \u044f\u043d\u0432\u0430\u0440\u044c;10(1):27-37. doi: 10.1016\/j.jchf.2021.08.007. Epub 2021 10 \u043d\u043e\u044f\u0431\u0440\u044f. \u0412\u0441\u0442\u0443\u043f\u043b\u0435\u043d\u0438\u0435 \u041f\u0430\u0446\u0438\u0435\u043d\u0442\u044b \u0441\u043e \u0441\u043d\u0438\u0436\u0435\u043d\u043d\u043e\u0439 \u0444\u0440\u0430\u043a\u0446\u0438\u0435\u0439 \u0432\u044b\u0431\u0440\u043e\u0441\u0430 (\u0424\u0412) \u0447\u0430\u0441\u0442\u043e \u0434\u0435\u043c\u043e\u043d\u0441\u0442\u0440\u0438\u0440\u0443\u044e\u0442 \u0443\u043b\u0443\u0447\u0448\u0435\u043d\u0438\u0435 \u0424\u0412 \u043b\u0435\u0432\u043e\u0433\u043e \u0436\u0435\u043b\u0443\u0434\u043e\u0447\u043a\u0430 (\u0424\u0412\u041b\u0416). \u041f\u0430\u0446\u0438\u0435\u043d\u0442\u044b, \u0443 \u043a\u043e\u0442\u043e\u0440\u044b\u0445 \u0424\u0412\u041b\u0416 \u0443\u0432\u0435\u043b\u0438\u0447\u0438\u0432\u0430\u0435\u0442\u0441\u044f \u0432 \u0430\u0431\u0441\u043e\u043b\u044e\u0442\u043d\u043e\u043c \u0432\u044b\u0440\u0430\u0436\u0435\u043d\u0438\u0438 \u043d\u0430 10% \u0438\u043b\u0438 \u226540% \u043f\u043e \u0441\u0440\u0430\u0432\u043d\u0435\u043d\u0438\u044e \u0441 \u0438\u0441\u0445\u043e\u0434\u043d\u044b\u043c \u0443\u0440\u043e\u0432\u043d\u0435\u043c\" \/>\n\t<meta name=\"robots\" content=\"max-image-preview:large\" \/>\n\t<meta name=\"author\" content=\"serene_admin\"\/>\n\t<meta name=\"google-site-verification\" content=\"E4w7Tq5OUsX4iPrZpEh5w3x9S4TTbvbUSzx6c5DiiDY\" \/>\n\t<meta name=\"yandex-verification\" content=\"4d7ed8a4cfca7240\" \/>\n\t<link rel=\"canonical\" href=\"https:\/\/www.serenepharma.com\/ru\/gazetaru\/prognosticheskoe-znachenie-globalnoj\/\" \/>\n\t<meta name=\"generator\" content=\"All in One SEO (AIOSEO) 4.9.10\" \/>\n\t\t<meta property=\"og:locale\" content=\"ru_RU\" \/>\n\t\t<meta property=\"og:site_name\" content=\"Serene - The Leading Pharmaceutical Company in Central Asia\" \/>\n\t\t<meta property=\"og:type\" content=\"article\" \/>\n\t\t<meta property=\"og:title\" content=\"\u041f\u0440\u043e\u0433\u043d\u043e\u0441\u0442\u0438\u0447\u0435\u0441\u043a\u043e\u0435 \u0437\u043d\u0430\u0447\u0435\u043d\u0438\u0435 \u0433\u043b\u043e\u0431\u0430\u043b\u044c\u043d\u043e\u0439 \u043f\u0440\u043e\u0434\u043e\u043b\u044c\u043d\u043e\u0439 \u0434\u0435\u0444\u043e\u0440\u043c\u0430\u0446\u0438\u0438 \u0443 \u043f\u0430\u0446\u0438\u0435\u043d\u0442\u043e\u0432 \u0441 \u0441\u0435\u0440\u0434\u0435\u0447\u043d\u043e\u0439 \u043d\u0435\u0434\u043e\u0441\u0442\u0430\u0442\u043e\u0447\u043d\u043e\u0441\u0442\u044c\u044e \u0441 \u0443\u043b\u0443\u0447\u0448\u0435\u043d\u043d\u043e\u0439 \u0444\u0440\u0430\u043a\u0446\u0438\u0435\u0439 \u0432\u044b\u0431\u0440\u043e\u0441\u0430 - Serene\" \/>\n\t\t<meta property=\"og:description\" content=\"\u0421\u0441\u044b\u043b\u043a\u0430: \u0421\u0430\u0442\u0438\u0442 \u0414\u0436\u0430\u043d\u0432\u0430\u043d\u0438\u0448\u0441\u0442\u0430\u043f\u043e\u0440\u043d, \u0416\u0410\u041a\u041a \u0421\u0435\u0440\u0434\u0435\u0447\u043d\u0430\u044f \u043d\u0435\u0434\u043e\u0441\u0442\u0430\u0442\u043e\u0447\u043d\u043e\u0441\u0442\u044c. 2022 \u044f\u043d\u0432\u0430\u0440\u044c;10(1):27-37. doi: 10.1016\/j.jchf.2021.08.007. 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